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E’ POSSIBILE BLOCCARE LA DIFFUSIONE DELLE STAMINALI DEL TUMORE AL SENO

AND 'CAN STOP THE SPREAD OF BREAST CANCER STEM

A study by the Tufts University School of Medicine, published in the journal Proceedings of the National Academy of Sciences, says that stem cells in breast cancer , that 'the cell held responsible for their resistance to Current therapies that promote metastasis, are stimulated by estrogen through a process that reflects the normal development of stem cells. The interruption of this process could help researchers to stop the spread of cancer stem cells.

According Charlotte Kuperwasser, who coordinated the study was crucial to find that estrogen may promote the growth of breast cancer by modulating the proportion of stem cells in breast cancer. The researchers also discovered that cancer cells can communicate with sensitivity to tumor stem cells to regulate their numbers. Perto interrupting the interaction between populations of cancer cells was able to prevent tumor growth. Kuperwasser and researchers at MIT and Harvard have used a mouse model to examine the behavior of human breast tumor tissue using a method that mimics the human body better than in other mouse models the standard. The researchers first examined the effects of estrogen on the growth of stem cells for breast cancer, finding that hormones cause a 800% increase in the number of stem cells 'bad'. Stem cells in breast cancer have few receptors for estrogen and for this the researchers now suspect that the action of estrogen through a reporting mechanism from neighboring cells that express the receptors. Posted by
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on December 6, 2010 Source: http://www.sanitanews.it/quotidiano/intarticolo.php?id=4293&sendid=636